Ventromedial hypothalamic glucose sensing and glucose homeostasis vary throughout the estrous cycle
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چکیده
منابع مشابه
Glucose Sensing Neurons in the Ventromedial Hypothalamus
Neurons whose activity is regulated by glucose are found in a number of brain regions. Glucose-excited (GE) neurons increase while glucose-inhibited (GI) neurons decrease their action potential frequency as interstitial brain glucose levels increase. We hypothesize that these neurons evolved to sense and respond to severe energy deficit (e.g., fasting) that threatens the brains glucose supply. ...
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Neuronal circuits in the central nervous system play a critical role in orchestrating the control of glucose and energy homeostasis. Glucose, beside being a nutrient, is also a signal detected by several glucose-sensing units that are located at different anatomical sites and converge to the hypothalamus to cooperate with leptin and insulin in controlling the melanocortin pathway.
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ژورنال
عنوان ژورنال: Physiology & Behavior
سال: 2016
ISSN: 0031-9384
DOI: 10.1016/j.physbeh.2016.09.021